close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shcSqualene-hopene cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (724 aa)    
Predicted Functional Partners:
NIDE1238
Squalene synthase; Function of strongly homologous gene; enzyme.
 
 0.985
NIDE0891
Radical SAM protein; Function of strongly homologous gene; enzyme.
   
 0.930
NIDE0862
Putative Adenosylhomocysteine nucleosidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.863
NIDE1438
Homologs of previously reported genes of unknown function.
   
 
 0.855
NIDE1479
Conserved protein of unknown function, putative sterol desaturase; Homologs of previously reported genes of unknown function.
   
 
 0.855
NIDE0700
Putative Dihydroflavanol 4-reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.844
holA
Putative DNA polymerase III, delta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.785
NIDE0737
Homologs of previously reported genes of unknown function.
 
     0.715
yrbE
ABC transporter, membrane component, putative ATP-dependent toluene efflux transporter; Function of strongly homologous gene; transporter; Belongs to the MlaE permease family.
       0.637
cyp
Cytochrome P450; Function of strongly homologous gene; enzyme; Belongs to the cytochrome P450 family.
  
 
 0.587
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.