Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
shcSqualene-hopene cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (724 aa)    
Predicted Functional Partners:
NIDE1238
Squalene synthase; Function of strongly homologous gene; enzyme.
 
 0.985
NIDE0891
Radical SAM protein; Function of strongly homologous gene; enzyme.
   
 0.930
NIDE0862
Putative Adenosylhomocysteine nucleosidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.864
NIDE0700
Putative Dihydroflavanol 4-reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.828
NIDE0737
Homologs of previously reported genes of unknown function.
 
     0.720
NIDE1438
Homologs of previously reported genes of unknown function.
   
 
 0.692
NIDE1479
Conserved protein of unknown function, putative sterol desaturase; Homologs of previously reported genes of unknown function.
   
 
 0.692
yrbE
ABC transporter, membrane component, putative ATP-dependent toluene efflux transporter; Function of strongly homologous gene; transporter; Belongs to the MlaE permease family.
       0.625
NIDE1519
Putative Pytoene desaturase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.604
crtB
Phytoene synthase; Function of strongly homologous gene; enzyme.
 
  
 0.579
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.