close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0954Peptidase S1C, HtrA family; Function of strongly homologous gene; enzyme. (372 aa)    
Predicted Functional Partners:
NIDE0953
Conserved protein of unknown function, UPF0047; Homologs of previously reported genes of unknown function.
       0.827
NIDE0952
Protein of unknown function; No homology to any previously reported sequences.
       0.815
NIDE0955
Uncharacterized ATPase, AAA family; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family.
   
 0.780
NIDE3330
Conserved protein of unknown function, SDR family; Homologs of previously reported genes of unknown function; 7742302.
   
 0.692
NIDE0950
Conserved protein of unknown function, Nucleotide-binding histidine triad family protein; Homologs of previously reported genes of unknown function; 12119013, 1472710, 323207.
  
    0.562
NIDE0951
Exported protein of unknown function; No homology to any previously reported sequences.
       0.557
NIDE0956
Conserved protein of unknown function, putative proteasome component; Homologs of previously reported genes of unknown function; 7583123, 9765579.
       0.533
ubact
Protein of unknown function; May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes.
       0.529
NIDE0949
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.525
pan
Proteasome-associated ATPase; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family.
    
 0.505
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.