| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE0965 | NIDE0966 | NIDE0965 | NIDE0966 | Putative Hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.549 |
| NIDE0966 | NIDE0965 | NIDE0966 | NIDE0965 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.549 |
| NIDE0966 | NIDE3181 | NIDE0966 | NIDE3181 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Aldose 1-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.410 |
| NIDE0966 | metH | NIDE0966 | NIDE1868 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.685 |
| NIDE0966 | mtnA | NIDE0966 | NIDE2731 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.681 |
| NIDE0966 | nadE | NIDE0966 | NIDE1358 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.483 |
| NIDE0966 | pycB | NIDE0966 | NIDE1204 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyruvate carboxylase, subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.424 |
| NIDE0966 | rlp | NIDE0966 | NIDE1881 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme. | 0.690 |
| NIDE0966 | talC | NIDE0966 | NIDE0493 | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Transaldolase, putative Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.422 |
| NIDE3181 | NIDE0966 | NIDE3181 | NIDE0966 | Putative Aldose 1-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.410 |
| metH | NIDE0966 | NIDE1868 | NIDE0966 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.685 |
| metH | mtnA | NIDE1868 | NIDE2731 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.805 |
| metH | rlp | NIDE1868 | NIDE1881 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme. | 0.702 |
| mtnA | NIDE0966 | NIDE2731 | NIDE0966 | 5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.681 |
| mtnA | metH | NIDE2731 | NIDE1868 | 5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.805 |
| mtnA | rlp | NIDE2731 | NIDE1881 | 5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme. | 0.962 |
| nadE | NIDE0966 | NIDE1358 | NIDE0966 | NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.483 |
| pycB | NIDE0966 | NIDE1204 | NIDE0966 | Pyruvate carboxylase, subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.424 |
| rlp | NIDE0966 | NIDE1881 | NIDE0966 | Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme. | Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.690 |
| rlp | metH | NIDE1881 | NIDE1868 | Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.702 |