STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
porBPyruvate:ferredoxin oxidoreductase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (300 aa)    
Predicted Functional Partners:
porA
Pyruvate:ferredoxin oxidoreductase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.997
vorCD
2-ketoisovalerate ferredoxin reductase, fused gamma and delta subunit; Function of strongly homologous gene; enzyme.
 
 0.995
porC
Pyruvate:ferredoxin oxidoreductase gamma subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.992
forA
2-oxoglutarate:ferredoxin oxidoredutase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.971
forC
2-oxoglutarate:ferredoxin oxidoredutase gamma subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.969
vorA
2-ketoisovalerate ferredoxin reductase, alpha subunit; Function of strongly homologous gene; enzyme.
 
 0.964
porE
Pyruvate:ferredoxin oxidoreductase epsilon subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.922
accB
Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.910
NIDE3866
Putative Acyl-CoA synthetase (NDP forming); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.909
ppdK
Pyruvate, phosphate dikinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PEP-utilizing enzyme family.
    
 0.908
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.