STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1015Putative Cell shape-determining protein MreD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (166 aa)    
Predicted Functional Partners:
NIDE1014
Putative Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
 
 0.974
mreB
Cell shape determining protein MreB; Function of homologous gene experimentally demonstrated in an other organism; structure.
  
  
 0.857
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 0.797
mrdA
Penicillin-binding protein 2; Function of strongly homologous gene; enzyme.
  
  
 0.765
NIDE1012
Protein of unknown function, RDD family; No homology to any previously reported sequences.
       0.608
rng
Ribonuclease G; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.510
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
   
    0.458
NIDE1011
Putative Peptidyl-prolyl cis-trans isomerase D (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.436
cmk
Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
    0.430
NIDE1666
Homologs of previously reported genes of unknown function.
  
  
 0.426
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.