Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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bfrABacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (159 aa)    
Predicted Functional Partners:
bfrB
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
 
  
 
0.972
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.911
NIDE2061
Conserved protein of unknown function, contains FMN-binding split barrel; Homologs of previously reported genes of unknown function; 12686112.
     
  0.900
NIDE3169
Putative Bacterioferritin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
     
  0.900
NIDE4379
Conserved protein of unknown function, contains FMN-binding split barrel; Homologs of previously reported genes of unknown function; 11786019, 12686112, 15858270.
     
  0.900
NIDE3257
Putative Bacterioferritin-associated ferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
 
 0.768
pheT
Phenylalanyl-tRNA synthetase, beta subunit; Function of strongly homologous gene; enzyme.
      
 0.692
NIDE2120
Anti-sigma factor antagonist; Function of strongly homologous gene; regulator.
   
  
 0.523
NIDE2368
Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the anti-sigma-factor antagonist family.
   
  
 0.523
NIDE2369
Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the anti-sigma-factor antagonist family.
   
  
 0.523
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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