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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bfrABacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (159 aa)    
Predicted Functional Partners:
bfrB
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
 
  
 
0.973
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.912
NIDE3169
Putative Bacterioferritin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
     
  0.900
NIDE3257
Putative Bacterioferritin-associated ferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
 
 0.847
hflB
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
      
 0.715
ftsH
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
      
 0.715
udg-2
UDP-glucose 6-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.691
porD
Pyruvate:ferredoxin oxidoreductase delta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.689
NIDE2120
Anti-sigma factor antagonist; Function of strongly homologous gene; regulator.
   
  
 0.487
NIDE2368
Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the anti-sigma-factor antagonist family.
   
  
 0.487
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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