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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1024Protein of unknown function, putative HD-type Metal-dependent phosphohydrolase; No homology to any previously reported sequences. (251 aa)    
Predicted Functional Partners:
NIDE1228
Response regulator, contains GGDEF domain; Function of strongly homologous gene; regulator.
 
   
 0.955
NIDE0390
Putative Signal transduction response regulator, receiver and diguanylate cyclase domain (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   
 0.936
NIDE4156
Protein of unknown function, contains Diguanylate kinase domain; No homology to any previously reported sequences; 11682196, 15063857, 15306016, 15569936, 15716451.
 
 
 0.760
NIDE2310
Protein of unknown function, contains Diguanylate cyclase domain; No homology to any previously reported sequences; 11682196, 15063857, 15075296, 15306016, 15569936, 15716451, 16418169, 17010156, 7592388.
  
 
 0.697
NIDE2522
Sensory response regulator with diguanylate cyclase domain; Function of strongly homologous gene; regulator.
   
 0.681
NIDE1023
Protein of unknown function, putative AraC type transcriptional regulator; No homology to any previously reported sequences; 8516313, 9409145, 9600836, 9600837, 9724717.
       0.581
NIDE0815
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.522
NIDE1025
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.522
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.515
NIDE1354
Conserved protein of unknown function, contains GAF and ANTAR domain; Homologs of previously reported genes of unknown function; 11032796, 11796212, 12271124, 15341725, 9433123.
 
      0.485
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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