Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdmCO-methyltransferase; Function of strongly homologous gene; enzyme. (234 aa)    
Predicted Functional Partners:
fabG
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
   0.900
fabG5
3-oxoacyl-(acyl-carrier-protein) reductase; Function of strongly homologous gene; enzyme.
 
  
   0.899
NIDE0445
Short-chain dehydrogenase; Function of strongly homologous gene; enzyme.
 
  
   0.889
fabG3
3-oxoacyl-(acyl-carrier-protein) reductase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
      0.885
fabG2
3-oxoacyl-(acyl-carrier-protein) reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
   0.874
NIDE1043
Putative uncharacterized transporter yedA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   0.612
NIDE1041
Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
       0.580
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
      0.490
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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