close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1044Putative Oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (368 aa)    
Predicted Functional Partners:
NIDE0809
Homologs of previously reported genes of unknown function.
  
  
 0.725
NIDE1045
Homologs of previously reported genes of unknown function.
       0.723
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.662
NIDE3181
Putative Aldose 1-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.598
lysS
Lysyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.575
NIDE3400
Putative ABC-type sugar transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.541
NIDE3623
Putative 2,5-diketo-D-gluconic acid reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.503
arnB-2
UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.494
NIDE3399
Putative ABC-type sugar transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
   
 0.467
rfbE
CDP-tyvelose epimerase; Function of strongly homologous gene; enzyme.
  
  
 0.454
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (30%) [HD]