| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE1064 | NIDE1065 | NIDE1064 | NIDE1065 | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Protein of unknown function; No homology to any previously reported sequences. | 0.473 |
| NIDE1064 | NIDE4168 | NIDE1064 | NIDE4168 | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.407 |
| NIDE1064 | ftsH | NIDE1064 | NIDE2929 | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.428 |
| NIDE1064 | grpE | NIDE1064 | NIDE1729 | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | 0.542 |
| NIDE1064 | hflB | NIDE1064 | NIDE2737 | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.428 |
| NIDE1065 | NIDE1064 | NIDE1065 | NIDE1064 | Protein of unknown function; No homology to any previously reported sequences. | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.473 |
| NIDE4168 | NIDE1064 | NIDE4168 | NIDE1064 | Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.407 |
| NIDE4168 | ftsH | NIDE4168 | NIDE2929 | Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.400 |
| NIDE4168 | hflB | NIDE4168 | NIDE2737 | Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.400 |
| ftsH | NIDE1064 | NIDE2929 | NIDE1064 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.428 |
| ftsH | NIDE4168 | NIDE2929 | NIDE4168 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.400 |
| ftsH | grpE | NIDE2929 | NIDE1729 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | 0.426 |
| grpE | NIDE1064 | NIDE1729 | NIDE1064 | Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.542 |
| grpE | ftsH | NIDE1729 | NIDE2929 | Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.426 |
| grpE | hflB | NIDE1729 | NIDE2737 | Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.426 |
| hflB | NIDE1064 | NIDE2737 | NIDE1064 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative Peptidase M48, Ste24p family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.428 |
| hflB | NIDE4168 | NIDE2737 | NIDE4168 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.400 |
| hflB | grpE | NIDE2737 | NIDE1729 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...] | 0.426 |
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