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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (367 aa)    
Predicted Functional Partners:
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.
 
 0.999
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 0.997
sdhA-2
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit or L-aspartate oxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.919
NIDE1179
Protein of unknown function; No homology to any previously reported sequences.
  
    0.687
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.687
NIDE2398
Putative Serine acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.616
NIDE2689
Conserved protein of unknown function, putative Hexapeptide repeat transferase; Homologs of previously reported genes of unknown function; 7481807, 8293817.
  
    0.616
cysE
Serine O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.616
NIDE3328
Putative Serine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.616
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.552
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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