STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macBABC transporter, ATPase component, putative Macrolide export ATP-binding protein; Function of strongly homologous gene; enzyme. (236 aa)    
Predicted Functional Partners:
macC
ABC transporter, permease component, putative Macrolide export permease protein; Function of strongly homologous gene; transporter.
 
 0.997
NIDE3944
Putative ABC-type transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 0.990
macA
Efflux transporter, RND family, MFP subunit, putative Macrolide-specific efflux protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.953
NIDE3338
ABC-type transport system, ATP-binding component; Function of strongly homologous gene; transporter.
 
   
0.913
NIDE0667
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
 
 0.806
mdtC
Multidrug efflux system, subunit C; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.794
NIDE3943
RND-type efflux transporter, membrane-fusion protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.779
NIDE3435
ABC-type transport system, ATPase component; Function of strongly homologous gene; enzyme.
 
   
0.721
NIDE0666
ABC-type transport system, permease component; Function of strongly homologous gene; transporter.
 
 0.672
rlmN
Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
     
 0.667
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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