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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1096Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function; 14659697, 1882418, 7667876, 9482716. (466 aa)    
Predicted Functional Partners:
rsfS
Conserved protein of unknown function, Iojap family; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.827
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.812
NIDE2640
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 15189147, 1882418, 7667876, 7748903, 8690703, 9482716.
 
     0.644
proB
Glutamat 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.615
obgE
GTPase involved in DNA replication and ribosome assembly; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.615
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
       0.564
NIDE1580
Conserved exported protein of unknown function, putative LPS-assembly protein Imp; Homologs of previously reported genes of unknown function; 12724388, 16861298, 2547691, 7811102.
  
   
 0.532
NIDE3134
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 15451670, 7667876, 9482716.
  
 
   0.530
NIDE0948
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 11777911, 14659697, 15223324, 1882418, 7667876, 9482716.
  
     0.517
rpsU
30S ribosomal protein S21; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bS21 family.
  
     0.501
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.