Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
btuEPredicted Glutathione peroxidase; Function of strongly homologous gene; enzyme; Belongs to the glutathione peroxidase family. (165 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.850
ydiU
Conserved protein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
   
  
 0.818
NIDE1493
Putative Sensor histidine kinase with MCP region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      
 0.793
NIDE1875
Probable Peroxiredoxin; Function of strongly homologous gene; enzyme.
   
 
 0.764
cysK
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.694
NIDE4034
Putative Thioredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
   
 0.568
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.534
htpX
Probable Protease HtpX; Function of strongly homologous gene; enzyme.
  
  
 0.534
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.524
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.465
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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