Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE1238Squalene synthase; Function of strongly homologous gene; enzyme. (319 aa)    
Predicted Functional Partners:
shc
Squalene-hopene cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.985
ispA
Geranyltranstransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.
 
 0.921
NIDE3385
Polyprenyl-diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
 0.909
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 
 0.826
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.814
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.766
NIDE2591
Amine oxidase, flavin-containing; Function of strongly homologous gene; enzyme.
  
  
 0.746
NIDE1739
Putative Multidrug resistance protein NorM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
  
 0.732
rpsA
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
    0.684
NIDE1237
Conserved exported protein of unknown function, Cupredoxin family; Homologs of previously reported genes of unknown function; 1324168, 14673090, 6307356, 7592701, 8083153.
       0.623
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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