close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1238Squalene synthase; Function of strongly homologous gene; enzyme. (319 aa)    
Predicted Functional Partners:
shc
Squalene-hopene cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.985
ispA
Geranyltranstransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.
 
 0.919
NIDE3385
Polyprenyl-diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
 0.907
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.899
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 
 0.827
NIDE2591
Amine oxidase, flavin-containing; Function of strongly homologous gene; enzyme.
  
  
 0.805
NIDE0048
Putative Methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.776
NIDE2393
Protein of unknown function, putative Methyltransferase; No homology to any previously reported sequences.
    
 0.776
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.763
NIDE1739
Putative Multidrug resistance protein NorM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 
 0.759
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.