Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE1240Conserved protein of unknown function, putative 4Fe-4S ferredoxin; Homologs of previously reported genes of unknown function; 2600971, 3932661. (90 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.900
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
     
  0.900
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.900
hom
Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.900
cysK
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.801
NIDE1241
Protein of unknown function; No homology to any previously reported sequences.
       0.777
NIDE1242
Putative [2Fe-2S] ferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
     
 0.699
nuoE
NADH-quinone oxidoreductase, subunit E; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.687
fdsG
Formate dehydrogenase, gamma subunit; Function of strongly homologous gene; enzyme.
  
 
 0.687
NIDE1243
Protein of unknown function; No homology to any previously reported sequences.
       0.619
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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