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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1252Homologs of previously reported genes of unknown function. (303 aa)    
Predicted Functional Partners:
hflB
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.888
ftsH
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.888
NIDE3962
Putative Rhomboid serine protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.695
NIDE2007
Protein of unknown function; No homology to any previously reported sequences.
  
     0.595
NIDE0132
Homologs of previously reported genes of unknown function; 9714164, 9857196.
  
  
 0.531
NIDE1251
Putative Cytochrome c; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
       0.518
NIDE0499
Homologs of previously reported genes of unknown function.
  
     0.507
yjeF
Conserved protein of unknown function, putative Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydr [...]
 
  
 0.490
NIDE0955
Uncharacterized ATPase, AAA family; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family.
   
 
 0.477
pan
Proteasome-associated ATPase; Function of strongly homologous gene; enzyme; Belongs to the AAA ATPase family.
   
 
 0.477
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.