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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1354Conserved protein of unknown function, contains GAF and ANTAR domain; Homologs of previously reported genes of unknown function; 11032796, 11796212, 12271124, 15341725, 9433123. (419 aa)    
Predicted Functional Partners:
NIDE4176
Putative Uroporphyrinogen III synthase HemD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      0.885
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
       0.788
NIDE0222
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   0.562
NIDE1352
Putative Type IV pili biogenesis protein PilQ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
     0.511
NIDE3753
Hybrid sensor histidine kinase; Function of strongly homologous gene; enzyme.
 
   0.508
NIDE0687
Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator.
 
  
   0.502
NIDE1228
Response regulator, contains GGDEF domain; Function of strongly homologous gene; regulator.
 
    0.502
NIDE3593
Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   0.490
NIDE1024
Protein of unknown function, putative HD-type Metal-dependent phosphohydrolase; No homology to any previously reported sequences.
 
      0.485
NIDE1870
Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator.
 
  
   0.478
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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