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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amtBAmmonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. (442 aa)    
Predicted Functional Partners:
glnB
Nitrogen regulatory protein PII; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
 
 0.999
glnB-2
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
  
 
 0.985
glnB-3
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
  
 
 0.985
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.904
NIDE2522
Sensory response regulator with diguanylate cyclase domain; Function of strongly homologous gene; regulator.
 
    
 0.867
NIDE0390
Putative Signal transduction response regulator, receiver and diguanylate cyclase domain (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
      0.844
nirC
Nitrite transporter; Function of strongly homologous gene; transporter.
  
  
 0.830
glnD
Putative (Protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
     
 0.800
cynS
Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
     
 0.794
focA
Formate transporter; Function of strongly homologous gene; transporter.
   
  
 0.783
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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