Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amtBAmmonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. (442 aa)    
Predicted Functional Partners:
glnB
Nitrogen regulatory protein PII; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
 
 0.999
glnB-2
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
  
 
 0.977
glnB-3
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
  
 
 0.977
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.918
NIDE2522
Sensory response regulator with diguanylate cyclase domain; Function of strongly homologous gene; regulator.
 
    
 0.870
NIDE0390
Putative Signal transduction response regulator, receiver and diguanylate cyclase domain (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
      0.844
nirC
Nitrite transporter; Function of strongly homologous gene; transporter.
  
  
 0.843
cynS
Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
     
 0.837
focA
Formate transporter; Function of strongly homologous gene; transporter.
   
  
 0.825
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
      
 0.775
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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