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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirCNitrite transporter; Function of strongly homologous gene; transporter. (276 aa)    
Predicted Functional Partners:
cynS
Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
 
   
 0.905
nirA
Ferredoxin-nitrite reductase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
   
 0.872
amtB
Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.830
narK
Nitrate transporter; Function of strongly homologous gene; transporter.
     
 0.740
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.693
nusG
Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination.
      
 0.543
NIDE3498
Sigma-54 dependent transcriptional regulator (modular protein); Function of strongly homologous gene; regulator.
      
 0.499
NIDE1366
Protein of unknown function; No homology to any previously reported sequences.
       0.485
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.477
hemD
Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.
 
  
 0.475
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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