close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cynSCyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (146 aa)    
Predicted Functional Partners:
nirA
Ferredoxin-nitrite reductase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.909
nirC
Nitrite transporter; Function of strongly homologous gene; transporter.
 
   
 0.905
cah
Carbonic anhydrase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.900
cam
Carbonic anhydrase; Function of strongly homologous gene; enzyme.
     
  0.900
cam2
Carbonic anhydrase; Function of strongly homologous gene; enzyme.
     
  0.900
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.798
amtB
Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.794
NIDE3242
Putative Nitrite transporter NirC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.770
focA
Formate transporter; Function of strongly homologous gene; transporter.
 
   
 0.764
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.695
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.