close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yefMAntitoxin of toxin-antitoxin stability system; Antitoxin component of a type II toxin-antitoxin (TA) system. (98 aa)    
Predicted Functional Partners:
yoeB
Addiction module toxin YoeB; Function of homologous gene experimentally demonstrated in an other organism; factor.
  
 
 0.894
NIDE1372
Putative Cytotoxic translational repressor of toxin-antitoxin stability system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
   
 
 0.839
stbE
Addiction module toxin; Function of strongly homologous gene; cell process.
   
 
 0.770
NIDE2003
Addiction module toxin, Txe/YoeB family; Function of strongly homologous gene; cell process.
 
 
 0.713
higB
Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin.
      
 0.706
mazF
Toxin MazF; Toxic component of a type II toxin-antitoxin (TA) system.
     
 0.692
mazE
Antitoxin MazE; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.685
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
      
 0.651
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
      
 0.651
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
      
 0.651
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (26%) [HD]