| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE1376 | NIDE1772 | NIDE1376 | NIDE1772 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.496 |
| NIDE1376 | amtB | NIDE1376 | NIDE1360 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.494 |
| NIDE1376 | glnA | NIDE1376 | NIDE1363 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.870 |
| NIDE1376 | glnB | NIDE1376 | NIDE1361 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Nitrogen regulatory protein PII; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.853 |
| NIDE1376 | glnB-2 | NIDE1376 | NIDE1771 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator. | 0.828 |
| NIDE1376 | glnB-3 | NIDE1376 | NIDE4390 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator. | 0.828 |
| NIDE1376 | glnD | NIDE1376 | NIDE1362 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Putative (Protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.733 |
| NIDE1376 | glnEb | NIDE1376 | NIDE1377 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | (Glutamate-ammonia-ligase) adenylyltransferase, subunit B; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the [...] | 0.766 |
| NIDE1376 | gltB | NIDE1376 | NIDE3384 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.596 |
| NIDE1376 | nadE | NIDE1376 | NIDE1358 | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.584 |
| NIDE1772 | NIDE1376 | NIDE1772 | NIDE1376 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | 0.496 |
| NIDE1772 | amtB | NIDE1772 | NIDE1360 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.670 |
| NIDE1772 | glnA | NIDE1772 | NIDE1363 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.435 |
| NIDE1772 | glnB | NIDE1772 | NIDE1361 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nitrogen regulatory protein PII; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.586 |
| NIDE1772 | glnB-2 | NIDE1772 | NIDE1771 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator. | 0.787 |
| NIDE1772 | glnB-3 | NIDE1772 | NIDE4390 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator. | 0.586 |
| NIDE1772 | gltB | NIDE1772 | NIDE3384 | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.467 |
| amtB | NIDE1376 | NIDE1360 | NIDE1376 | Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...] | 0.494 |
| amtB | NIDE1772 | NIDE1360 | NIDE1772 | Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.670 |
| amtB | glnA | NIDE1360 | NIDE1363 | Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.904 |
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