Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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scpBSegregation and condensation protein B (modular protein); Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (301 aa)    
Predicted Functional Partners:
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.999
cmk
Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.837
smc
Putative Chromosome segregation protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 
 0.815
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.804
engA
GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.757
NIDE2595
Pseudouridine synthase, rsuA family; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.661
rluB
23S rRNA pseudouridylate synthase B (modular protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.617
rluE
23S rRNA pseudouridylate synthase E; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.617
NIDE3971
Putative Pseudouridine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.617
NIDE1416
Protein of unknown function; No homology to any previously reported sequences.
  
    0.611
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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