NIDE1420 protein (Nitrospira defluvii) - STRING interaction network

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Score

NIDE1420

Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812. (989 aa)

Predicted Functional Partners:

guaB

0.712

NIDE1742

0.647

NIDE2162

0.594

guaA

0.488

tktA

0.442

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE1420	NIDE1742	NIDE1420	NIDE1742	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.647
NIDE1420	NIDE2162	NIDE1420	NIDE2162	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.594
NIDE1420	guaA	NIDE1420	NIDE1422	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.488
NIDE1420	guaB	NIDE1420	NIDE1421	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.712
NIDE1420	tktA	NIDE1420	NIDE2536	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.442
NIDE1742	NIDE1420	NIDE1742	NIDE1420	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	0.647
NIDE1742	NIDE2162	NIDE1742	NIDE2162	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.948
NIDE1742	guaB	NIDE1742	NIDE1421	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.402
NIDE2162	NIDE1420	NIDE2162	NIDE1420	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	0.594
NIDE2162	NIDE1742	NIDE2162	NIDE1742	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.948
guaA	NIDE1420	NIDE1422	NIDE1420	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	0.488
guaA	guaB	NIDE1422	NIDE1421	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	tktA	NIDE1422	NIDE2536	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.482
guaB	NIDE1420	NIDE1421	NIDE1420	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	0.712
guaB	NIDE1742	NIDE1421	NIDE1742	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.402
guaB	guaA	NIDE1421	NIDE1422	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.999
guaB	tktA	NIDE1421	NIDE2536	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.861
tktA	NIDE1420	NIDE2536	NIDE1420	Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Protein of unknown function, contains NHL repeats; No homology to any previously reported sequences; 10518528, 15136047, 2169613, 7528812.	0.442
tktA	guaA	NIDE2536	NIDE1422	Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.482
tktA	guaB	NIDE2536	NIDE1421	Transketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.861

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