Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
istA-2Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (445 aa)    
Predicted Functional Partners:
istB1
Insertion sequence IS21 putative ATP-binding protein; Function of strongly homologous gene; extrachromosomal origin.
 
 0.990
istB
Insertion sequence IS21 putative ATP-binding protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.959
istB3
Insertion sequence IS21 putative ATP-binding protein; Function of strongly homologous gene; extrachromosomal origin.
   0.811
istB4
Insertion sequence IS21 ATP-binding protein; Function of strongly homologous gene; extrachromosomal origin.
   0.808
rbr
Rubrerythrin; Function of strongly homologous gene; factor.
      
 0.733
porB2-N
Partial 2-oxoacid:ferredoxin oxidoreductase beta subunit (fragment N-terminal); Function of strongly homologous gene; enzyme.
       0.658
porB2-C
Partial 2-oxoacid:ferredoxin oxidoreductase beta subunit (fragment C-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.553
forB2
2-oxoacid:ferredoxin oxidoreductase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.444
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.424
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.