STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crtBPhytoene synthase; Function of strongly homologous gene; enzyme. (303 aa)    
Predicted Functional Partners:
NIDE1519
Putative Pytoene desaturase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.980
ispA
Geranyltranstransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.
 
 0.919
NIDE3385
Polyprenyl-diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
 0.907
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.899
NIDE2591
Amine oxidase, flavin-containing; Function of strongly homologous gene; enzyme.
 
  
 0.868
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 
 0.827
NIDE1521
ABC-type transport system, periplasmic binding component; Function of strongly homologous gene; transporter.
       0.825
NIDE1522
Putative Beta-phosphoglucomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.816
waaA
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
      
 0.777
NIDE0048
Putative Methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.776
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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