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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1523Protein of unknown function; No homology to any previously reported sequences; 14731533, 15335710, 1639195, 7531822, 7953536. (254 aa)    
Predicted Functional Partners:
NIDE0325
Putative RNA-metabolising metallo-beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.944
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.944
NIDE3222
Putative Deacetylase, histone deacetylase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.910
NIDE0128
Putative DEAD/DEAH box helicase, SNF2 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.808
flgM
Anti-sigma 28 factor FlgM; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 
 0.789
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.764
NIDE0832
Protein of unknown function, putative Protein tyrosine phosphatase; No homology to any previously reported sequences; 14739250, 1650499, 2550140, 8987394, 9646865, 9818190.
   
 0.759
NIDE2619
Conserved protein of unknown function, putative dual specificity protein phosphatase; Homologs of previously reported genes of unknown function; 12678841, 9818190.
   
 0.759
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.741
rpoZ
DNA-directed RNA polymerase, omega subunit (modular protein); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
  0.740
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.