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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas3CRISPR-associated helicase Cas3; Function of strongly homologous gene; cell process. (909 aa)    
Predicted Functional Partners:
NIDE1542
Putative CRISPR-associated protein Cse1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
 
 
 0.994
cse4
CRISPR-associated protein Cse4; Function of strongly homologous gene; cell process.
 
 
 0.991
cas5e
CRISPR-associated protein Cas5e; Function of strongly homologous gene; cell process.
 
 
 0.991
NIDE1544
Putative CRISPR-associated protein Cse2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
 
  
 0.952
cse3
CRISPR-associated protein Cse3; Function of strongly homologous gene; cell process.
 
   
 0.932
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.925
cas2
CRISPR-associated protein Cas2; Function of strongly homologous gene; cell process.
 
  
 0.917
NIDE1540
Protein of unknown function; No homology to any previously reported sequences.
       0.526
NIDE1539
Protein of unknown function; No homology to any previously reported sequences.
       0.467
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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