STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cse3CRISPR-associated protein Cse3; Function of strongly homologous gene; cell process. (232 aa)    
Predicted Functional Partners:
cas5e
CRISPR-associated protein Cas5e; Function of strongly homologous gene; cell process.
  
 0.986
cse4
CRISPR-associated protein Cse4; Function of strongly homologous gene; cell process.
 
  
 0.958
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.948
cas2
CRISPR-associated protein Cas2; Function of strongly homologous gene; cell process.
 
   
 0.943
NIDE1544
Putative CRISPR-associated protein Cse2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
 
   
 0.940
NIDE1542
Putative CRISPR-associated protein Cse1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
 
  
 0.934
cas3
CRISPR-associated helicase Cas3; Function of strongly homologous gene; cell process.
 
   
 0.932
NIDE1540
Protein of unknown function; No homology to any previously reported sequences.
       0.425
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.