STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1569Putative C4-dicarboxylate transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (470 aa)    
Predicted Functional Partners:
putA
Bifunctional protein PutA; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
   
  
 0.801
NIDE3595
Na+/solute symporter; Function of strongly homologous gene; transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.563
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.551
NIDE1568
Protein of unknown function; No homology to any previously reported sequences.
       0.527
cstA
Carbon starvation protein; Function of homologous gene experimentally demonstrated in an other organism; phenotype.
 
  
 0.520
aclA
ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.494
NIDE0542
Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences.
     
 0.490
NIDE4168
Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.473
NIDE1570
Homologs of previously reported genes of unknown function; 9514722.
       0.461
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.456
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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