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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1576Putative cAMP phosphodiesterase, class-II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (262 aa)    
Predicted Functional Partners:
NIDE2630
Protein of unknown function, putative Protease with integrin domain; No homology to any previously reported sequences; 11517925, 7845208, 8439290.
   
   0.822
accD
Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
       0.757
NIDE1578
Protein of unknown function; No homology to any previously reported sequences.
       0.757
NIDE1116
Putative Adenylate cyclase with CHASE2 sensor domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.609
folC
Bifunctional protein FolC: Folylpolyglutamate synthase and Dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family.
  
    0.581
NIDE1580
Conserved exported protein of unknown function, putative LPS-assembly protein Imp; Homologs of previously reported genes of unknown function; 12724388, 16861298, 2547691, 7811102.
       0.575
NIDE1870
Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator.
      0.521
NIDE1150
Uncharacterized protein; Homologs of previously reported genes of unknown function; 14722619, 9478130; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.493
NIDE2820
Homologs of previously reported genes of unknown function.
  
     0.458
NIDE1575
Putative Nickel/cobalt efflux system RcnA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the NiCoT transporter (TC 2.A.52) family.
       0.449
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.