close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1580Conserved exported protein of unknown function, putative LPS-assembly protein Imp; Homologs of previously reported genes of unknown function; 12724388, 16861298, 2547691, 7811102. (827 aa)    
Predicted Functional Partners:
NIDE1342
Homologs of previously reported genes of unknown function.
 
 
 0.905
folC
Bifunctional protein FolC: Folylpolyglutamate synthase and Dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family.
       0.827
NIDE3044
Putative Outer membrane protein assembly factor YaeT precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
  
 0.752
NIDE1222
Sensor histidine kinase; Function of strongly homologous gene; enzyme.
  
     0.713
NIDE0853
Protein of unknown function, TPR-like; No homology to any previously reported sequences.
 
  
 0.712
NIDE0540
Putative Outer membrane lipoprotein carrier protein LolA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
   
 0.675
accD
Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
       0.663
NIDE0491
Homologs of previously reported genes of unknown function.
  
     0.652
tolB
Protein TolB precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.616
lolC
Lipoprotein-releasing system, transmembrane protein LolC; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
   
 0.611
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.