Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE1586Putative Histidine kinase, contains GAF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (426 aa)    
Predicted Functional Partners:
NIDE1859
Membrane protein of unknown function, putative Response regulator with Hpt domain; No homology to any previously reported sequences; 11406410, 11489844, 11934609, 14636076, 1482126, 16176121, 18076326, 7699720.
 
 
 0.901
NIDE2070
Protein of unknown function, putative Response regulator with PAS domain S-box; No homology to any previously reported sequences; 14982921, 15009198, 16176121, 18076326, 7699720, 9301332, 9382818.
 
 
   0.872
NIDE1585
Sigma-54 dependent transcriptional regulator; Function of strongly homologous gene; regulator.
 
 
   0.856
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.832
NIDE0858
Putative Phosphate regulon transcriptional regulatory protein phoB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   0.830
phoB
Phosphate regulon transcriptional regulator PhoB; Function of strongly homologous gene; regulator.
 
   0.829
NIDE0815
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.827
NIDE1858
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
   0.824
NIDE2412
Signal transduction response regulator; Function of strongly homologous gene; regulator.
  
   0.823
NIDE1229
Response regulator; Function of strongly homologous gene; regulator.
  
   0.822
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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