Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpoERNA polymerase sigma 24 (sigma E) factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)    
Predicted Functional Partners:
NIDE1608
Putative Glycosyl hydrolase, family 13; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.806
NIDE0047
Nitroreductase; Function of strongly homologous gene; enzyme.
      
 0.760
rpoH
RNA polymerase, sigma 32 (sigma H) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
   
  
 0.759
degP
Serine protease Do; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.754
degP-2
Protease Do; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.754
NIDE1609
Putative Glycosyl hydrolase, family 13; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.668
clpP
ATP-dependent Clp protease, proteolytic subunit clpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.658
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
      
 0.649
cydA
Cytochrome bd oxidase, subunit I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
      
 0.627
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.599
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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