Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
ppdKPyruvate, phosphate dikinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PEP-utilizing enzyme family. (949 aa)    
Predicted Functional Partners:
pycB
Pyruvate carboxylase, subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.962
pgk
Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family.
    
 0.954
vorCD
2-ketoisovalerate ferredoxin reductase, fused gamma and delta subunit; Function of strongly homologous gene; enzyme.
    
 0.931
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.927
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.924
pycA
Pyruvate carboxylase, subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.918
maeA2
NAD-dependent malic enzyme; Function of strongly homologous gene; enzyme.
   
 
 0.913
forC
2-oxoglutarate:ferredoxin oxidoredutase gamma subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.912
forA
2-oxoglutarate:ferredoxin oxidoredutase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.912
porC
Pyruvate:ferredoxin oxidoreductase gamma subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.912
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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