Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE1669Putative Pyruvate decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (550 aa)    
Predicted Functional Partners:
yccW
Putative Methyltransferase with PUA domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.548
oliA
Oligopeptide transporter; Function of strongly homologous gene; transporter.
       0.539
hisI
Fused Phosphoribosyl-AMP cyclohydrolase and Phosphoribosyl-ATP diphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family.
    
   0.504
ilvH
Acetolactate synthase, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.476
NIDE1668
Protein of unknown function; No homology to any previously reported sequences.
       0.448
NIDE3623
Putative 2,5-diketo-D-gluconic acid reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
   
 0.427
NIDE0356
Putative Glucose-6-phosphate isomerase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GPI family.
   
 
 0.425
putA
Bifunctional protein PutA; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
  
 
 0.420
ilvD
Dihydroxy-acid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family.
  
   
 0.420
pgk
Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family.
   
 
 0.404
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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