Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acrB2RND-type permease AcrB; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1089 aa)    
Predicted Functional Partners:
NIDE1686
Putative Membrane-fusion protein of multidrug efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  0.995
NIDE0727
Putative Acriflavine resistance protein acrA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.957
NIDE1685
Putative Outer membrane protein TolC precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.933
NIDE2164
Putative Multidrug efflux transporter, membrane fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.923
NIDE3917
RND-type efflux transporter, membrane-fusion protein; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.921
NIDE3494
Putative RND efflux system, membrane fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.892
ttgA
RND efflux system, membrane fusion protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   
  0.859
NIDE1688
DNA-binding response regulator, CheY like; Function of strongly homologous gene; regulator.
       0.786
NIDE2718
Putative Outer membrane efflux protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  0.752
NIDE1803
Putative Acriflavine resistance protein A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.718
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.