dnaK protein (Nitrospira defluvii) - STRING interaction network

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Score

dnaK

Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (643 aa)

Predicted Functional Partners:

dnaJ

0.997

grpE

0.996

cbpA

0.994

groL

0.990

NIDE1156

0.984

groS

0.959

NIDE3177

0.951

clpV1

0.943

clpB2

0.943

clpB3

0.943

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE1156	clpB2	NIDE1156	NIDE2263	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.604
NIDE1156	clpB3	NIDE1156	NIDE2457	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Chaperone protein ClpB; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the ClpA/ClpB family.	0.604
NIDE1156	clpV1	NIDE1156	NIDE1985	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Type VI secretion ATPase, ClpV1 family; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family.	0.604
NIDE1156	dnaK	NIDE1156	NIDE1728	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.984
NIDE1156	groL	NIDE1156	NIDE1378	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.831
NIDE1156	groS	NIDE1156	NIDE1379	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.648
NIDE1156	grpE	NIDE1156	NIDE1729	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 15170475, 8016869, 8302830.	Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...]	0.914
NIDE3177	clpB2	NIDE3177	NIDE2263	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.624
NIDE3177	clpB3	NIDE3177	NIDE2457	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Chaperone protein ClpB; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the ClpA/ClpB family.	0.624
NIDE3177	clpV1	NIDE3177	NIDE1985	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Type VI secretion ATPase, ClpV1 family; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family.	0.624
NIDE3177	dnaK	NIDE3177	NIDE1728	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.951
NIDE3177	groL	NIDE3177	NIDE1378	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.723
NIDE3177	groS	NIDE3177	NIDE1379	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.549
NIDE3177	grpE	NIDE3177	NIDE1729	Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.	Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...]	0.819
cbpA	clpB2	NIDE3402	NIDE2263	Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.622
cbpA	clpB3	NIDE3402	NIDE2457	Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	Chaperone protein ClpB; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the ClpA/ClpB family.	0.604
cbpA	clpV1	NIDE3402	NIDE1985	Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	Type VI secretion ATPase, ClpV1 family; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family.	0.604
cbpA	dnaK	NIDE3402	NIDE1728	Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.994
cbpA	groL	NIDE3402	NIDE1378	Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.795
cbpA	groS	NIDE3402	NIDE1379	Curved DNA-binding protein CbpA; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.861