Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (162 aa)    
Predicted Functional Partners:
hisI
Fused Phosphoribosyl-AMP cyclohydrolase and Phosphoribosyl-ATP diphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family.
   
  
 0.940
tilS
tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 0.861
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
 
 0.806
NIDE0691
Putative 3-methyladenine DNA glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DNA glycosylase MPG family.
 
  
 0.742
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
 0.706
NIDE1731
Putative Biotin-(acetyl-CoA-carboxylase) ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.657
xylB
Aryl-alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.643
NIDE1747
Putative RNA polymerase sigma factor, sigma-24 homolog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.580
NIDE1746
Homologs of previously reported genes of unknown function.
       0.558
NIDE1678
Putative Peptidase M22; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.557
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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