glnB-2 protein (Nitrospira defluvii) - STRING interaction network

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glnB-2

Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator. (107 aa)

Predicted Functional Partners:

amtB

0.985

NIDE1770

0.913

glnA

0.845

argB

0.843

glnD

0.843

NIDE1376

0.828

NIDE1772

0.787

NIDE4388

0.780

NIDE1769

0.706

NIDE0047

0.700

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE0047	glnB-2	NIDE0047	NIDE1771	Nitroreductase; Function of strongly homologous gene; enzyme.	Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.	0.700
NIDE1376	NIDE1772	NIDE1376	NIDE1772	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.496
NIDE1376	amtB	NIDE1376	NIDE1360	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.	0.494
NIDE1376	glnA	NIDE1376	NIDE1363	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.870
NIDE1376	glnB-2	NIDE1376	NIDE1771	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.	0.828
NIDE1376	glnD	NIDE1376	NIDE1362	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	Putative (Protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	0.733
NIDE1769	NIDE1770	NIDE1769	NIDE1770	Putative NADH-quinone oxidoreductase, subunit L (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.	0.914
NIDE1769	NIDE4388	NIDE1769	NIDE4388	Putative NADH-quinone oxidoreductase, subunit L (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.	0.707
NIDE1769	glnB-2	NIDE1769	NIDE1771	Putative NADH-quinone oxidoreductase, subunit L (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.	0.706
NIDE1770	NIDE1769	NIDE1770	NIDE1769	Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.	Putative NADH-quinone oxidoreductase, subunit L (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.914
NIDE1770	glnB-2	NIDE1770	NIDE1771	Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.	Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.	0.913
NIDE1772	NIDE1376	NIDE1772	NIDE1376	Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	0.496
NIDE1772	amtB	NIDE1772	NIDE1360	Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.	0.670
NIDE1772	glnA	NIDE1772	NIDE1363	Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.435
NIDE1772	glnB-2	NIDE1772	NIDE1771	Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.	0.787
NIDE4388	NIDE1769	NIDE4388	NIDE1769	Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.	Putative NADH-quinone oxidoreductase, subunit L (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.707
NIDE4388	glnB-2	NIDE4388	NIDE1771	Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.	Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.	0.780
amtB	NIDE1376	NIDE1360	NIDE1376	Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.	Putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (modular protein); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulator [...]	0.494
amtB	NIDE1772	NIDE1360	NIDE1772	Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.	Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.670
amtB	glnA	NIDE1360	NIDE1363	Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.	Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.904