close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1793Exported protein of unknown function; No homology to any previously reported sequences. (343 aa)    
Predicted Functional Partners:
yaeQ
Homologs of previously reported genes of unknown function; 9604894.
   
    0.815
NIDE3501
Homologs of previously reported genes of unknown function.
   
    0.726
phoU
Phosphate transport system protein PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.534
lepB
Signal peptidase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family.
   
    0.534
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
   
    0.489
cspB
Cold shock protein modulated with ribosomal subunit interface-like protein; Function of strongly homologous gene; factor.
   
    0.445
yfcH
Conserved protein of unknown function, NAD(P)-binding Rossmann-fold domain; Homologs of previously reported genes of unknown function.
   
    0.434
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
    0.433
fabG3
3-oxoacyl-(acyl-carrier-protein) reductase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.432
NIDE1202
Putative Thiol peroxidase (modular protein); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
    0.430
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.