| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE1742 | NIDE2672 | NIDE1742 | NIDE2672 | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Vitamin B12 import system, ATP-binding protein BtuD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.560 |
| NIDE1742 | cspA | NIDE1742 | NIDE2641 | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.466 |
| NIDE1742 | lipA | NIDE1742 | NIDE3950 | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.410 |
| NIDE1742 | msbA | NIDE1742 | NIDE1807 | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.590 |
| NIDE2672 | NIDE1742 | NIDE2672 | NIDE1742 | Putative Vitamin B12 import system, ATP-binding protein BtuD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.560 |
| NIDE2672 | msbA | NIDE2672 | NIDE1807 | Putative Vitamin B12 import system, ATP-binding protein BtuD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.606 |
| NIDE4273 | msbA | NIDE4273 | NIDE1807 | Putative ABC-type transport system, ATPase and permease components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.934 |
| cspA | NIDE1742 | NIDE2641 | NIDE1742 | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.466 |
| cspA | infA | NIDE2641 | NIDE1334 | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.829 |
| cspA | lipA | NIDE2641 | NIDE3950 | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.644 |
| cspA | mdtC | NIDE2641 | NIDE3527 | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | Multidrug efflux system, subunit C; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.428 |
| cspA | msbA | NIDE2641 | NIDE1807 | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.658 |
| cspA | rlmN | NIDE2641 | NIDE3728 | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.622 |
| def1 | msbA | NIDE1806 | NIDE1807 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.665 |
| infA | cspA | NIDE1334 | NIDE2641 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.829 |
| infA | lipA | NIDE1334 | NIDE3950 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.755 |
| infA | mdtC | NIDE1334 | NIDE3527 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Multidrug efflux system, subunit C; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.740 |
| infA | msbA | NIDE1334 | NIDE1807 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Lipid A export ATP-binding/permease protein MsbA; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.755 |
| infA | rlmN | NIDE1334 | NIDE3728 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.768 |
| lipA | NIDE1742 | NIDE3950 | NIDE1742 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.410 |