Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
moeBMolybdopterin biosynthesis protein MoeB; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (267 aa)    
Predicted Functional Partners:
moaD
Molybdopterin converting factor, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.992
NIDE1818
Putative Molybdopterin converting factor, small subunit MoaD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 0.992
moaE
Molybdopterin converting factor, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.969
NIDE1815
Homologs of previously reported genes of unknown function; 9605331.
 
 
 0.958
thiF
Adenylyltransferase ThiF; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 
0.956
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.956
NIDE1822
Putative Thiamine biosynthesis protein ThiS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
 
 
 0.930
NIDE3481
Homologs of previously reported genes of unknown function.
  
 0.928
NIDE4045
Conserved protein of unknown function, putative sulfur carrier ThiS; Homologs of previously reported genes of unknown function; 15362849, 6388576.
  
 0.928
NIDE3717
Putative Thiosulfate sulfurtransferase GlpE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.905
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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