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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1817Homologs of previously reported genes of unknown function. (79 aa)    
Predicted Functional Partners:
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.948
NIDE1818
Putative Molybdopterin converting factor, small subunit MoaD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.941
thrC1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
   
 0.934
hom
Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.918
cysK
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.912
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
     
 0.907
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
  0.902
NIDE1240
Conserved protein of unknown function, putative 4Fe-4S ferredoxin; Homologs of previously reported genes of unknown function; 2600971, 3932661.
     
  0.900
thiF
Adenylyltransferase ThiF; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.808
NIDE4260
Putative Formate hydrogenlyase, small subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
   0.808
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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