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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpSATP-dependent Clp protease adapter protein ClpS; Function of strongly homologous gene; regulator; Belongs to the ClpS family. (97 aa)    
Predicted Functional Partners:
clpV1
Type VI secretion ATPase, ClpV1 family; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family.
  
 
 0.879
clpB2
Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.879
clpB3
Chaperone protein ClpB; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the ClpA/ClpB family.
  
 
 0.879
clpP
ATP-dependent Clp protease, proteolytic subunit clpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.839
NIDE0563
Radical SAM superfamily protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.727
NIDE1848
Homologs of previously reported genes of unknown function.
  
     0.704
NIDE1172
Conserved membrane protein of unknown function (modular protein); Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
  
     0.668
NIDE1945
Exported protein of unknown function, contains haemagglutination activity domain; No homology to any previously reported sequences; 15079085, 16339899, 7519681.
  
    0.664
NIDE1946
Protein of unknown function, putative exoprotein of filamentous haemagglutinin family; No homology to any previously reported sequences; 16339899, 2539596, 7519681, 9724625.
  
    0.661
NIDE0553
Conserved protein of unknown function, filamentous haemagglutinin family; Homologs of previously reported genes of unknown function; 15079085, 16339899, 7519681.
  
    0.634
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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