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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1873Conserved exported protein of unknown function, DUF748; Homologs of previously reported genes of unknown function. (982 aa)    
Predicted Functional Partners:
NIDE2802
Homologs of previously reported genes of unknown function.
  
     0.589
NIDE2604
Putative Lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.
  
     0.487
NIDE3249
Putative Heavy metal efflux system, outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  
 0.483
NIDE3133
Homologs of previously reported genes of unknown function.
  
     0.436
NIDE2068
Conserved protein of unknown function, DUF1458; Homologs of previously reported genes of unknown function; 17027852.
   
    0.428
NIDE3612
Homologs of previously reported genes of unknown function.
  
     0.420
rdgB
Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.417
NIDE1767
Putative Cation efflux system protein CzcC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  
 0.416
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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