Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1875Probable Peroxiredoxin; Function of strongly homologous gene; enzyme. (211 aa)    
Predicted Functional Partners:
NIDE4034
Putative Thioredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
 0.947
trxB
Thioredoxin-disulfide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.895
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.790
hscA
Chaperone protein HscA (Hsc66); Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the heat shock protein 70 family.
   
 
 0.790
btuE
Predicted Glutathione peroxidase; Function of strongly homologous gene; enzyme; Belongs to the glutathione peroxidase family.
   
 
 0.764
recQ
ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
   0.738
NIDE1906
Putative Metallophosphoesterase, possible DNA repair exonuclease SbcCD, subunit D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.726
NIDE3177
Protein of unknown function, contains DnaJ domain; No homology to any previously reported sequences; 12454054, 15170475, 8016869, 9644977.
   
 
 0.725
NIDE4190
Protein of unknown function; No homology to any previously reported sequences.
   
 
 0.681
fur
Ferric uptake regulation protein; Function of strongly homologous gene; regulator; Belongs to the Fur family.
  
  
 0.645
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.