Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE1879Putative Metal dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (448 aa)    
Predicted Functional Partners:
NIDE0687
Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator.
 
  
 0.759
NIDE2522
Sensory response regulator with diguanylate cyclase domain; Function of strongly homologous gene; regulator.
 
   
 0.731
NIDE4156
Protein of unknown function, contains Diguanylate kinase domain; No homology to any previously reported sequences; 11682196, 15063857, 15306016, 15569936, 15716451.
  
 
 0.725
NIDE2310
Protein of unknown function, contains Diguanylate cyclase domain; No homology to any previously reported sequences; 11682196, 15063857, 15075296, 15306016, 15569936, 15716451, 16418169, 17010156, 7592388.
  
 
 0.692
NIDE0390
Putative Signal transduction response regulator, receiver and diguanylate cyclase domain (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
   
 0.665
NIDE1584
Putative Response regulator with HD domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
 0.644
NIDE1878
Conserved protein of unknown function, radical SAM; Homologs of previously reported genes of unknown function; 14633981.
       0.578
NIDE1880
Protein of unknown function; No homology to any previously reported sequences.
       0.560
NIDE1228
Response regulator, contains GGDEF domain; Function of strongly homologous gene; regulator.
  
   
 0.515
NIDE1756
Homologs of previously reported genes of unknown function.
  
   0.474
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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