Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrBMethionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (139 aa)    
Predicted Functional Partners:
msrA-2
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.989
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.988
btuE
Predicted Glutathione peroxidase; Function of strongly homologous gene; enzyme; Belongs to the glutathione peroxidase family.
  
  
 0.850
ydiU
Conserved protein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
     
 0.844
NIDE1493
Putative Sensor histidine kinase with MCP region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      
 0.793
tolR
Protein TolR; Function of homologous gene experimentally demonstrated in an other organism; transporter.
      
 0.757
arsR
Arsenical resistance operon repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.
      
 0.739
yccU
Conserved protein of unknown function, CoA binding protein; Homologs of previously reported genes of unknown function.
 
      0.713
gcvT
Aminomethyltransferase, glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
   
  
 0.680
smbP
Metal-binding protein SmbP; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.655
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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